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What are the common pharmaceutical intermediates? List of pharmaceutical intermediates.

What are the common pharmaceutical intermediates? Pharmaceutical intermediates refer to chemical raw materials or chemical products used in the process of drug synthesis. Judging from the development history of my country’s pharmaceutical intermediates industry, after nearly 30 years of development, pharmaceutical intermediates have developed from a small branch of the chemical industry to an emerging industry with an output value of several billion yuan, and its market competition has become increasingly fierce. The following editor will introduce you to several common pharmaceutical intermediates:

N-benzyl-N-methylethanolamine

N-benzyl-N-methylethanolamine is an important pharmaceutical intermediate, which can synthesize anti-asthma and anti-allergic drugs, anti-hypertensive drug nicardipine and some new drugs for the treatment of cardiovascular diseases; in addition, it can also synthesize pesticides, herbicides and plants. Bactericides and metal preservatives, etc.

4,4’-Dimethoxymethyl acetoacetate

Methyl 4,4′-Dimethoxyacetoacetate is an intermediate of the important cardio-cerebrovascular disease treatment drug nilvadipine. It is currently the leading cardio-cerebrovascular disease treatment drug in the international market, and it has not been produced in China. Using glyoxylic acid as raw material and trimethyl orthoformate in the presence of concentrated sulfuric acid to synthesize methyl dimethoxyacetate, which reacts with methyl acetate and sodium methoxide to obtain methyl 4,4′-dimethoxyacetoacetate ester.

α-Methylene cyclic ketone

α-Methylene cyclic ketone is the active center of many anti-cancer active drugs. It contains α, β-unsaturated ketone structure, which is a hidden group of anti-cancer active groups, and has become important for the synthesis of many important cyclic anti-cancer drugs. Intermediate.

4-Propylthio-o-phenylenediamine

4-Propylthio-o-phenylenediamine is a key intermediate of a high-efficiency broad-spectrum insect repellent drug albendazole. Albendazole is a new drug that was only marketed in the late 1980s. It has low toxicity to humans and animals and is a benzo Imidazole drugs are the strongest in Chinese medicine. 

Pazopanib

Pazopanib is a new oral angiogenesis inhibitor developed by GlaxoSmithKline that can interfere with the formation of new blood vessels required for the survival and growth of intractable tumors. It targets the vascular endothelial growth factor receptor (VEGFR). It works by inhibiting the formation of new blood vessels supplying the tumor. It is suitable for the treatment of advanced renal cell carcinoma (a type of kidney cancer in which cancer cells are found in the renal tubules), soft tissue sarcoma (STS), epithelial ovarian cancer and non-small cell lung cancer (NSCLC).

2,4-Dichloro-5-methoxyaniline

Bosutinib, developed by Wyeth Pharmaceuticals in the United States, was approved by the European Union in September 2010 as an “orphan drug” for the treatment of chronic myelogenous leukemia (CML). On September 4, 2012, the drug was approved by the U.S. Food and Drug Administration (FDA) to be marketed under the trade name Bosulif. The European Food and Drug Administration (EMA) approved the listing on March 27, 2013, and the Japanese PMDA approved listing on September 26, 2014. 

Pharmaceutical intermediates list from manufacturer

We manufacture intermediates for several API’s falling under a wide range of therapeutic categories. We also manufacture fine chemicals & Specialty chemicals. We are among the largest manufacturer of pharma intermediates products in China and we have an extensive range of different pharmaceutical intermediates, intermediate pharma, pharmaceutical formulation intermediates and medical intermediate.

Pharmaceutical intermediates list

 

Sr. No.

Product Name

CAS No.

Description

1

5-Ethyl pyridine-2-ethanol

5223-6-3

Pioglitazone HCL is Anti-Diabetic drug.

2

Alpha-d-glucofuranose,1,2-0-(2,2,2-trichloroethylidene)-,(r)

15879-93-3

It is used in formulation of Avicide & rodenticide.

3

2,4-Thiazolidinedione

2295-31-0

Pioglitazone HCL is Anti-Diabetic drug.

4

1-Phenyl-1-Cyclopentanecarboxylic Acid (1P1C)

77-55-4

Pentoxyverine Citrate & Carbetapentane is used to treat cough that is caused by the common cold, flu or allergies.

5

6-Nitro-7-chloro-4-hydroxy quinazoline

53449-14-2

Afatinib is used to treat a certain type of lung cancer (non-small cell lung cancer) that has spread to other parts of the body. It belongs to a class of drugs known as kinase inhibitors. It works by slowing or stopping the growth of cancer cells.

6

Camphorquinone

10373-78-1

It is used in making Dental care products.

7

1,1-Diphenylacetone

781-35-1

It is used as pharmaceutical Intermediate.

8

Anthranilamide

88-68-6

Acetaldehyde scavending Agent in PET Bottles.

9

4-Aminoacetanilide

122-80-5

This product is used as General Industrial Fine Chemical in Dyes & Pigment Industries.

10

2-Iodophenol

533-58-4

It is used as pharmaceutical Intermediate.

11

2-Nitrothiophene

609-40-5

It is used as pharmaceutical Intermediate.

12

2-Iodothiophene

3437-95-4

It is used as pharmaceutical Intermediate.

13

2,4-Dimethylpyrrole

625-82-1

It is used in Electronic industry.

14

2,6-Dichloroisonicotinic acid (2,6-Dichloropyridine-4-carboxylic acid)

5398-44-7

It is used as pharmaceutical Intermediate.

15

3,5-Dinitroaniline

618-87-1

It is used in Electronic industry.

16

3,5-Dinitrosalicylic acid

609-99-4

It is used as pharmaceutical Intermediate.

17

3-Bromoacetylpyridine HBr

17694-68-7

It is used as pharmaceutical Intermediate.

18

4-Methoxybenzylamine

2393-23-9

It is used to treat acute myelogenous leukemia ( a type of cancer of the white blood cells) in combination with other medications.

19

4-Aminobenzoic acid

150-13-0

It is used as pharmaceutical Intermediate.

20

4-Acetylbenzonitrile

1443-80-7

It is used as pharmaceutical Intermediate.

21

4-(2-Chloroethyl) morpholine HCl

3647-69-6

It is used as pharmaceutical Intermediate.

22

4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide (TFMSAA)

654-62-6

It is used as pharmaceutical Intermediate.

23

Benzoic Hydrazide

613-94-5

It is used as pharmaceutical Intermediate.

24

Aminodiphenylmethane (BENZHYD)

91-00-9

It is used as pharmaceutical Intermediate.

25

Benzophenoneimine

1013-88-3

It is used as pharmaceutical Intermediate.

26

Diphenyl Diselenide

1666-13-3

It is used as pharmaceutical Intermediate.

27

Diphenic Acid (Biphenyl-2,2’dicarboxylic Acid)

482-05-3

It is used as pharmaceutical Intermediate.

28

Diphenylamine

122-39-4

It is used as pharmaceutical Intermediate.

29

Homophthalic Acid

89-51-0

It is used in Electronic industry.

30

n-Heptylamine

111-68-2

Ibutilide can aggravate or induce serious cardiac arrhythmias, and use of the drug requires both a proper environment to administer treatment and care in optimal patient selection for treatment.

31

Pyridinium p-toluenesulfonate

24057-28-1

Carbetapentane is used to treat cough that is caused by the common cold, flu, or allergies.

32

Pentaerythrityl Tetraacetate

597-71-7

It is used as pharmaceutical Intermediate.

33

Pentaerythritol Tetrabenzoate

4196-86-5

It is used as pharmaceutical Intermediate.

34

Sodium Nitroprusside

13755-38-9

It is used as pharmaceutical Intermediate.

 

Frequently Asked Questions regarding pharmaceutical intermediates

What are pharmaceutical intermediates?

Pharmaceutical intermediates are chemicals compounds widely used in manufacturing various types of drug in bulk quantity also used for research and development by Pharmaceutical and biopharma companies.

 

Which is the best Pharmaceutical intermediates manufacturer in China?

Sarex is one of the leading manufacturer intermediates for several API’s falling under a wide range of therapeutic categories. We also manufacture fine chemicals & Specialty chemicals. Contact us now!

 

Why choose Tengyu for best active pharmaceutical ingredients (API) and Pharmaceutical intermediates?

Tengyy is among the largest manufacturer of 5-Ethyl pyridine-2-ethanol products in India and we offers an extensive range of different active pharmaceutical ingredients (API) and Pharmaceutical intermediates. Check out our range of API & pharmaceutical intermediates and Enquire Now!

 

What procedure should I follow to enquire for Pharmaceutical intermediates?

You can easily enquire for any Pharmaceutical intermediates using our contact us & enquiry form. You need to mention the pharmaceutical intermediates chemical name or let us know your application, our expert can suggest the best based your applications and requirements.

 

What are the types of pharmaceutical intermediates does Tengyu offers?

Tengyu Offers extensive range of different pharmaceutical intermediates. Every intermediates of pharmaceutical have different uses and applications. Check out our range of pharmaceutical intermediates and Enquire Now!

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